1. DRMS enhancer regulation

Understanding the activating signals and repressive mechanisms that act on DRMS enhancers to direct regenerative gene expression.

2. Identification of regeneration enhancers

Using whole-genome approaches to identify and characterize DRMS enhancers and their regulatory targets.

3. Tissue-level identification of regeneration factors

Using our unique ablation and expression genetic system to identify and characterize novel factors required for regeneration.

4. Exploring tissue necrosis and regeneration

Understanding how different types of injury, such as necrosis, can lead to a regeneration via necrosis-induced apoptosis (NiA).